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Biological Chemistry

2017

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Function and Inhibition of Protein-only Ribonuclease P

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[kinetic mechanism of protein-only ribonuclease P, inhibition of protein-only RNase P, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：2 下载：0]
Structural and Biochemical Characterization of the Early Steps in Fungal Indole Alkaloid Biosynthesis

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[prenylated indole alkaloids, bicyclo[2.2.2]diazaoctane, intramolecular Diels-Alder reaction, malbrancheamide biosynthesis, Biological Chemistry, Science, Biological Chemistry]

预览 | 原文链接 [浏览：4 下载：0]
Understanding Protein Folding Mechanisms of Chaperone Proteins Using Cryo-EM

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Cryo-EM of Chaperone Proteins, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：3 下载：2]
Vacuolar Proteases of Saccharomyces cerevisiae: Characterization of an Overlooked Homolog Leads to New Functional Insights

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Autophagy, Vacuole, Molecular biology, Yeast, Saccharomyces cerevisiae, Hydrolases, Biological Chemistry, Genetics, Molecular, Cellular and Developmental Biology, Science (General), Health Sciences, Science, Molecular, Cellular, and Developmental Biology]

预览 | 原文链接 [浏览：23 下载：32]
Investigations into the Stucture and Function of Type I Polyketide Synthases

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[natural products biosynthesis, Biological Chemistry, Science, Cancer Biology]

预览 | 原文链接 [浏览：14 下载：6]
Toward Molecularly Targeted Therapies for Renal Disease

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Pax2, paired domain, drug discovery, high-throughput screen, virtual screen, kidney disease, Biological Chemistry, Genetics, Molecular, Cellular and Developmental Biology, Science (General), Science, Molecular & Cellular Pathology]

预览 | 原文链接 [浏览：25 下载：25]
Computational Modeling of Protein Structure, Function, and Binding Hotspots

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[MixMD, Mixed-solvent molecular dynamics, Biological Chemistry, Science, Biophysics]

预览 | 原文链接 [浏览：11 下载：15]
Investigating Endothelial Dysfunction in a CRISPR/Cas9 Model of Fabry Disease

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Fabry disease, Endothelial dysfunction, Biological Chemistry, Molecular, Cellular and Developmental Biology, Pharmacy and Pharmacology, Physiology, Science (General), Health Sciences, Science, Pharmacology]

预览 | 原文链接 [浏览：7 下载：14]
Functional Analysis of Early Core Region Modification in the LPS of Gram-negative Bacteria

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Lipopolysaccharide, Gram-negative, Membrane sciences, Glycolipids, Biological Chemistry, Microbiology and Immunology, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：52 下载：19]
Understanding HDAC8-Catalyzed Deacetylation:From New Substrates to Diseases

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Histone deacetylase 8, protein substrates, Chemical Biology, Acetylation, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：26 下载：17]