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Biological Chemistry

2016

<符合条件的数据共：23条>

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Targeting the menin-MLL-LEDGF Interaction with Small Molecule Inhibitors.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Small molecule inhibitors, protein-protein interaction, Biological Chemistry, Science, Molecular & Cellular Pathology]

预览 | 原文链接 [浏览：3 下载：1]
Substrate Recognition by Protein-only Ribonuclease Ps

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Ribonuclease P, RNase P, PRORP, Biological Chemistry, Science, Biological Chemistry]

预览 | 原文链接 [浏览：23 下载：1]
Structural and Functional Studies of Gaq Signaling and Regulation.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[p63RhoGEF, G[alpha]q, x-ray crystallography, nuclear magnetic resonance, regulator of g protein signaling, small-angle x-ray scattering, Biological Chemistry, Science (General), Science, Biophysics]

预览 | 原文链接 [浏览：14 下载：9]
Template Based Modeling and Structural Refinement of Protein-Protein Interactions.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Protein structure prediction., Protein protein interactions., Biological Chemistry, Science, Bioinformatics]

预览 | 原文链接 [浏览：51 下载：0]
Structural and Functional Insights into the Type II Secretion System of Vibrio cholerae.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Microbiology, Zinc, Type II Secretion, Protein, Biological Chemistry, Microbiology and Immunology, Science (General), Health Sciences, Science, Microbiology and Immunology]

预览 | 原文链接 [浏览：36 下载：17]
Unlocking an HDAC Toolbox: Methods toward Understanding Isozyme-specific Activity.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Histone Deacetylase 8, Histone Deacetylase 11, HDAC, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：15 下载：11]
Peptidyl-Prolyl Isomerases as Promising Targets for Natural Product-Inspired Therapeutics.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Natural-product inspired therapeutics, Peptidyl-prolyl isomerases (PPIases) as promising drug targets, Enhanced pharmacological properties of bifunctional molecules, Semisynthetic modification of macrolide immunosuppressants, Biological Chemistry, Science, Biological Chemistry]

预览 | 原文链接 [浏览：14 下载：0]
Heat Shock Protein 70 (Hsp70) Acts as a Guardian Against Multiple Cell Death Pathways.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Chemical Probes Against Hsp70 Reveal Cytoprotective Activities, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：11 下载：0]
Mechanistic and Structural Insights into the Chemical Modulation of Amyloid Aggregation

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Protein Aggregation, Amyloids, Alzheimer", s disease, Biological Chemistry, Chemistry, Science, Chemistry]

预览 | 原文链接 [浏览：26 下载：20]
Fluorescent Labeling, Co-Tracking, and Quantification of RNA In Cellulo.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Intracellular Single-Molecule Fluorescence Microscopy of RNA, RNA Induced Silencing Complex, microRNA, Fluorescent labeling of mRNA, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：29 下载：14]