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Science

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Development of a Chemoproteomic Approach to Study Kinase-Substrate Interactions and the Discovery of CDK4 as a 4E-BP1 Kinase

颁布单位：[University of Michigan] | 颁布时间：2019 | 实施时间：2019 | 学科分类：[Kinase, Chemoproteomics, Cap-dependent Translation, CDK4, Cell Cycle, Biological Chemistry, Molecular, Cellular and Developmental Biology, Chemistry, Science (General), Health Sciences, Science, Chemical Biology]

预览 | 原文链接 [浏览：35 下载：8]
Structure, Function, and Inhibition of Protein Depalmitoylases

颁布单位：[University of Michigan] | 颁布时间：2018 | 实施时间：2018 | 学科分类：[palmitoylation, proteomics, chemical biology, inhibitors, Biological Chemistry, Science (General), Science, Chemical Biology]

预览 | 原文链接 [浏览：31 下载：45]
Expression and Characterization of HgcA and HgcB, Two Proteins Involved in Methylmercury Biosynthesis

颁布单位：[University of Michigan] | 颁布时间：2018 | 实施时间：2018 | 学科分类：[methylmercury, biogeochemistry, mercury binding protein, environmental toxic element cycles, iron-sulfur protein, cobalamin (vitamin B12), Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：15 下载：14]
Adaptation of Chemical Biology Approaches for Dissecting Disordered Protein Dynamics

颁布单位：[University of Michigan] | 颁布时间：2018 | 实施时间：2018 | 学科分类：[IDP, Intrinsically Disordered Proteins, Protein Dynamics, Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：20 下载：29]
Structural Studies and Pharmacological Targeting of Protein Kinases in Obesity and Heart Disease

颁布单位：[University of Michigan] | 颁布时间：2018 | 实施时间：2018 | 学科分类：[Kinase, X-ray crystallography, Adrenergic receptor signaling, Structure-based drug design, Biological Chemistry, Chemistry, Molecular, Cellular and Developmental Biology, Science, Chemical Biology]

预览 | 原文链接 [浏览：41 下载：13]
Exploration of the Disambiguation of Amino Acid Types to Chi-1 Rotamer Types inProtein Structure Prediction and Design

颁布单位：[University of Michigan] | 颁布时间：2018 | 实施时间：2018 | 学科分类：[Protein Design, Protein Informatics, Structural Biology, Bioinformatics, Science (General), Science, Chemical Biology]

预览 | 原文链接 [浏览：37 下载：1]
The PH Domain as a Mediator of G?? Effector Interactions

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Regulation of phospholipase C beta, G protein-coupled receptor kinase, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：19 下载：13]
Function and Inhibition of Protein-only Ribonuclease P

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[kinetic mechanism of protein-only ribonuclease P, inhibition of protein-only RNase P, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：15 下载：0]
Modulating the Global Conformations of c-Src Kinase

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Kinase, c-Src, Conformation, Medicinal Chemistry, Chemical Biology, Biological Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：38 下载：96]
Structural Characterization of Dynamic Protein Machines by Cryo-electron Microscopy

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Electron Microscopy, Chaperones, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：57 下载：96]