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Biological Chemistry

2017

<符合条件的数据共：24条>

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Development, Synthesis, and Characterization of G Protein-Coupled Receptor Kinase Inhibitors Using Structure Based Drug Design for the Advancement of Heart Failure Therapeutics

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Medicinal Chemistry, GRK Inhibitors, Heart Failure Therapeutics, G-protein couple receptor kinases, Structural Biology, Biological Chemistry, Pharmacy and Pharmacology, Chemistry, Health Sciences, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：15 下载：8]
Investigations into the Stucture and Function of Type I Polyketide Synthases

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[natural products biosynthesis, Biological Chemistry, Science, Cancer Biology]

预览 | 原文链接 [浏览：15 下载：6]
The PH Domain as a Mediator of G?? Effector Interactions

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Regulation of phospholipase C beta, G protein-coupled receptor kinase, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：19 下载：13]
Understanding HDAC8-Catalyzed Deacetylation:From New Substrates to Diseases

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Histone deacetylase 8, protein substrates, Chemical Biology, Acetylation, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：27 下载：24]
Quality Control Mechanisms of Molecular Chaperones in the Folding and Degradation of Client Proteins

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Molecular chaperone proteins, Biological Chemistry, Science, Biological Chemistry]

预览 | 原文链接 [浏览：28 下载：16]
Structural and Biochemical Characterization of the Early Steps in Fungal Indole Alkaloid Biosynthesis

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[prenylated indole alkaloids, bicyclo[2.2.2]diazaoctane, intramolecular Diels-Alder reaction, malbrancheamide biosynthesis, Biological Chemistry, Science, Biological Chemistry]

预览 | 原文链接 [浏览：19 下载：0]
Function and Inhibition of Protein-only Ribonuclease P

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[kinetic mechanism of protein-only ribonuclease P, inhibition of protein-only RNase P, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：15 下载：0]
Identification and Evaluation of Bacterial RNA Polymerase Inhibitors Using a Novel Plasmid-based Transcription Assay

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[RNA polymerase, transcription, drug discovery, rifampin, high-throughput screen, tuberculosis, Biological Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：38 下载：6]
Toward Molecularly Targeted Therapies for Renal Disease

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Pax2, paired domain, drug discovery, high-throughput screen, virtual screen, kidney disease, Biological Chemistry, Genetics, Molecular, Cellular and Developmental Biology, Science (General), Science, Molecular & Cellular Pathology]

预览 | 原文链接 [浏览：28 下载：25]
Modulating the Global Conformations of c-Src Kinase

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Kinase, c-Src, Conformation, Medicinal Chemistry, Chemical Biology, Biological Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：38 下载：96]