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Biological Chemistry

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Immobilized Enzymes: Activity, Orientation, and Stability.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Immobilized enzymes, Nitroreductase, Self-assembling monolayers, Enzyme kinetics, Enzyme stability, Enzyme orientation, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：45 下载：34]
Chemical Modulators of Heat Shock Protein 70 (Hsp70) Validate this Molecular Chaperone as a Target for Tauopathy

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Hsp70, Biological Chemistry, Chemistry, Molecular, Cellular and Developmental Biology, Science (General), Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：14 下载：22]
Mechanistic and Structural Insights into the Chemical Modulation of Amyloid Aggregation

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Protein Aggregation, Amyloids, Alzheimer", s disease, Biological Chemistry, Chemistry, Science, Chemistry]

预览 | 原文链接 [浏览：30 下载：26]
Probing the Mechanisms of Aldehyde Decarbonylation Using Radical Clock Substrate Analogues.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Radical Clock, Aldehyde Decarbonylation, Biofuel, Biological Chemistry, Science, Biological Chemistry]

预览 | 原文链接 [浏览：41 下载：9]
Peptidyl-Prolyl Isomerases as Promising Targets for Natural Product-Inspired Therapeutics.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Natural-product inspired therapeutics, Peptidyl-prolyl isomerases (PPIases) as promising drug targets, Enhanced pharmacological properties of bifunctional molecules, Semisynthetic modification of macrolide immunosuppressants, Biological Chemistry, Science, Biological Chemistry]

预览 | 原文链接 [浏览：18 下载：21]
An Antibiotic Discovery Campaign Targeting VirF, the Main Transcriptional Regulator of Virulence in Shigella flexneri

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Antibiotic Discovery Campaign, Shigella, Anti-virulence, VirF, Biological Chemistry, Microbiology and Immunology, Pharmacy and Pharmacology, Chemistry, Science (General), Health Sciences, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：31 下载：28]
Structural and Functional Studies of Gaq Signaling and Regulation.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[p63RhoGEF, G[alpha]q, x-ray crystallography, nuclear magnetic resonance, regulator of g protein signaling, small-angle x-ray scattering, Biological Chemistry, Science (General), Science, Biophysics]

预览 | 原文链接 [浏览：16 下载：9]
Characterization on the Structure and Dynamics of Protein-Protein Complexes Between Cytochrome P450 and its Redox Partners.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[membrane protein, cytochrome P450, cytochrome P450 reductase, cytochrome b5, membrane, NMR, Biological Chemistry, Science, Chemistry]

预览 | 原文链接 [浏览：37 下载：29]
Template Based Modeling and Structural Refinement of Protein-Protein Interactions.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Protein structure prediction., Protein protein interactions., Biological Chemistry, Science, Bioinformatics]

预览 | 原文链接 [浏览：55 下载：17]
Mechanistic and Structural Insights into the Chemical Modulation of Amyloid Aggregation

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Protein Aggregation, Amyloids, Alzheimer", s disease, Biological Chemistry, Chemistry, Science, Chemistry]

预览 | 原文链接 [浏览：21 下载：22]