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Biological Chemistry

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Investigations into the Stucture and Function of Type I Polyketide Synthases

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[natural products biosynthesis, Biological Chemistry, Science, Cancer Biology]

预览 | 原文链接 [浏览：17 下载：6]
Function and Inhibition of Protein-only Ribonuclease P

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[kinetic mechanism of protein-only ribonuclease P, inhibition of protein-only RNase P, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：17 下载：0]
Template Based Modeling and Structural Refinement of Protein-Protein Interactions.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Protein structure prediction., Protein protein interactions., Biological Chemistry, Science, Bioinformatics]

预览 | 原文链接 [浏览：55 下载：17]
Mechanistic and Structural Insights into the Chemical Modulation of Amyloid Aggregation

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Protein Aggregation, Amyloids, Alzheimer", s disease, Biological Chemistry, Chemistry, Science, Chemistry]

预览 | 原文链接 [浏览：21 下载：22]
Unlocking an HDAC Toolbox: Methods toward Understanding Isozyme-specific Activity.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Histone Deacetylase 8, Histone Deacetylase 11, HDAC, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：17 下载：11]
Characterization on the Structure and Dynamics of Protein-Protein Complexes Between Cytochrome P450 and its Redox Partners.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[membrane protein, cytochrome P450, cytochrome P450 reductase, cytochrome b5, membrane, NMR, Biological Chemistry, Science, Chemistry]

预览 | 原文链接 [浏览：37 下载：29]
Chemical Modulators of Heat Shock Protein 70 (Hsp70) Validate this Molecular Chaperone as a Target for Tauopathy

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Hsp70, Biological Chemistry, Chemistry, Molecular, Cellular and Developmental Biology, Science (General), Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：16 下载：22]
Probing the Mechanisms of Aldehyde Decarbonylation Using Radical Clock Substrate Analogues.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Radical Clock, Aldehyde Decarbonylation, Biofuel, Biological Chemistry, Science, Biological Chemistry]

预览 | 原文链接 [浏览：41 下载：9]
Targeting the Activator Interaction Domain of Mediator Subunit Med25.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Protein-protein interactions, Chemical Biology, High-throughput screening, Natural Products, Transcription, Biological Chemistry, Chemistry, Science, Chemistry]

预览 | 原文链接 [浏览：40 下载：99]
Targeting the menin-MLL-LEDGF Interaction with Small Molecule Inhibitors.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Small molecule inhibitors, protein-protein interaction, Biological Chemistry, Science, Molecular & Cellular Pathology]

预览 | 原文链接 [浏览：24 下载：1]