分类导航

效力级别
发布时间

2019(2)

2018(4)

2017(8)

2016(5)

2015(5)

2014(7)

2013(6)

2012(6)

2011(2)

2010(3)

更多
发布机构

University of ...(52)
学科类别

Medicinal Chemistry(52)

Science(52)

Chemistry(37)

Biological Chemistry(26)

Health Sciences(14)

Science (General)(13)

Pharmacy and Pharmacology(12)

Cancer(4)

Computational Chemistry(3)

Oncology and Hematology(3)

更多
文种类型
地区
时效性

检索结果

已选条件:

Medicinal Chemistry

<符合条件的数据共：52条>

排序方式

登录后可批量下载(统一登录，激活码登录)

Structure-Based Design, Synthesis and Evaluation of Novel and Selective Small-Molecule Inhibitors of the Anti-Apoptotic Protein Mcl-1.

颁布单位：[University of Michigan] | 颁布时间：2014 | 实施时间：2014 | 学科分类：[Anti-apoptotic Mcl-1, Medicinal Chemistry, Protein-protein Interaction Inhibitor, Cancer, Protein NMR Spectroscopy, Structure-activity Relationship, Biological Chemistry, Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：21 下载：2]
Phage Display as a Tool for Probing Lipid A Biosynthesis.

颁布单位：[University of Michigan] | 颁布时间：2013 | 实施时间：2013 | 学科分类：[Lipid A, Phage Display, LpxA, LpxD, Escherichia Coli, Biological Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：49 下载：58]
Development of a Novel Class of Multifunctional Virulence-Attenuating Antibiotics.

颁布单位：[University of Michigan] | 颁布时间：2013 | 实施时间：2013 | 学科分类：[Antibiotics, Group a Streptococcus, Structure Activity Relationship, Macromolecular Target Identification, Biofilm Inhibition, Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：42 下载：2]
Incorporation of Protein Flexibility in Structure-Based Drug Discovery of HIV-1 Protease and Bacterial Hsp70 Chaperone.

颁布单位：[University of Michigan] | 颁布时间：2013 | 实施时间：2013 | 学科分类：[Medicinal Chemistry, Computational Chemistry, Protein Dynamics, Drug Discovery, HIV Protease, Heat Shock Protein 70 Hsp70 Chaperone, Biological Chemistry, Pharmacy and Pharmacology, Chemistry, Science (General), Health Sciences, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：31 下载：12]
Molecular Recognition of Small Molecules by Rho-associated Kinase.

颁布单位：[University of Michigan] | 颁布时间：2013 | 实施时间：2013 | 学科分类：[Lead Optimization, Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：9 下载：12]
The Mu and Delta Opioid Receptors:Mixed Efficacy Ligands and Receptor Trafficking.

颁布单位：[University of Michigan] | 颁布时间：2013 | 实施时间：2013 | 学科分类：[Interactions of Mu and Delta Opioid Receptors, Biological Chemistry, Pharmacy and Pharmacology, Science (General), Health Sciences, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：50 下载：1]
Synthetic and Biocatalytic Methods for the Chemoenzymatic Production of Novel Cryptophycin Anticancer Agents.

颁布单位：[University of Michigan] | 颁布时间：2013 | 实施时间：2013 | 学科分类：[Medicinal Chemistry, Cancer, Cryptophycin, Natural Products, Chemoenzymatic, Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：20 下载：4]
Substrate Specificity of Metal-Dependent Lysine Deacetylases.

颁布单位：[University of Michigan] | 颁布时间：2012 | 实施时间：2012 | 学科分类：[KDAC8, KDAC11, Biological Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：16 下载：3]
Synthesis of Tritium Labeled Queuine, PreQ1 and Related Azide Probes TowardExamining the Prevalence of Queuine.

颁布单位：[University of Michigan] | 颁布时间：2012 | 实施时间：2012 | 学科分类：[Queuine, PreQ1, Synthesis of Pyrrolopyrimidine, Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：34 下载：24]
Understanding and Developing PikC as a Tool in Organic Synthesis. Part I: Total Synthesis of Methymycin and Neomethymycin Featuring a Catalytic Nickel Ynal Cyclization and a Biocatalytic PikC CH Oxidation. Part II: Regiodivergent Nickel Catalyzed Macrocyc

颁布单位：[University of Michigan] | 颁布时间：2012 | 实施时间：2012 | 学科分类：[Nickel Catalyzed Macrocyclization, Methymycin and NeomethymycinTotal Synthesis, Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：12 下载：0]