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Biological Chemistry

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Structural and Biochemical Studies of the Initiation Steps in Three Natural Product Biosynthetic Pathways

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Natural Products, Olefin Synthase, Apratoxin, Cahuitamycin, Initiation of Natural Product Biosynthesis, 1-nonadecene, Biological Chemistry, Science, Biological Chemistry]

预览 | 原文链接 [浏览：9 下载：1]
Optimization of Acidic Post-translational Modification Detection and Natural Product Biosynthetic Enzyme Analysis with Dual Polarity nLC/FT-ICR Mass Spectrometry

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Mass Spectrometry, Nanoflow Liquid Chromatography, Nanoelectrospray Ionization, Phosphopeptides, Sulfopeptides, Natural Product Biosynthesis, Biological Chemistry, Chemistry, Science, Chemistry]

预览 | 原文链接 [浏览：32 下载：3]
Decoding the Bio-Assembly of Hapalindole-Type Alkaloids from Cyanobacteria for Drug Discovery

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[biosynthetic pathway, hapalindole-type alkaloids, cyanobacteria, natural products, Cope rearrangement, drug discovery, Biological Chemistry, Chemistry, Genetics, Natural Resources and Environment, Science (General), Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：26 下载：2]
Modulating the Global Conformations of c-Src Kinase

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Kinase, c-Src, Conformation, Medicinal Chemistry, Chemical Biology, Biological Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：35 下载：86]
Structure and Biochemistry of Cytochromes P450 Involved in the Biosynthesis of Macrolide Antibiotics

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Cytochrome P450, Macrolide antibiotics, Natural products, Biosynthesis, Biological Chemistry, Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：24 下载：3]
Development, Synthesis, and Characterization of G Protein-Coupled Receptor Kinase Inhibitors Using Structure Based Drug Design for the Advancement of Heart Failure Therapeutics

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Medicinal Chemistry, GRK Inhibitors, Heart Failure Therapeutics, G-protein couple receptor kinases, Structural Biology, Biological Chemistry, Pharmacy and Pharmacology, Chemistry, Health Sciences, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：15 下载：8]
Understanding Protein Folding Mechanisms of Chaperone Proteins Using Cryo-EM

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Cryo-EM of Chaperone Proteins, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：10 下载：2]
Toward Molecularly Targeted Therapies for Renal Disease

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Pax2, paired domain, drug discovery, high-throughput screen, virtual screen, kidney disease, Biological Chemistry, Genetics, Molecular, Cellular and Developmental Biology, Science (General), Science, Molecular & Cellular Pathology]

预览 | 原文链接 [浏览：26 下载：25]
Investigations into the Stucture and Function of Type I Polyketide Synthases

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[natural products biosynthesis, Biological Chemistry, Science, Cancer Biology]

预览 | 原文链接 [浏览：15 下载：6]
Understanding HDAC8-Catalyzed Deacetylation:From New Substrates to Diseases

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Histone deacetylase 8, protein substrates, Chemical Biology, Acetylation, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：27 下载：17]