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Science (General)

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Chemical Modulators of Heat Shock Protein 70 (Hsp70) Validate this Molecular Chaperone as a Target for Tauopathy

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Hsp70, Biological Chemistry, Chemistry, Molecular, Cellular and Developmental Biology, Science (General), Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：11 下载：22]
Modifying Gelators for Sensing Applications and Developing Online Resources for Organic Courses.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Low molecular weight gels, Online homework, Chemical education, Supramolecular chemistry, Chemistry, Science (General), Science, Chemistry]

预览 | 原文链接 [浏览：15 下载：10]
Disruption of Endosomal Membrane by Cationic Vectors Drives Endosomal Release and Enables Successful Gene Delivery

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Gene delivery, Gene therapy, Endosomal escape, Drug delivery, Proton sponge, siRNA delivery, Biomedical Engineering, Biological Chemistry, Chemistry, Science (General), Engineering, Health Sciences, Science, Biomedical Engineering]

预览 | 原文链接 [浏览：22 下载：16]
The Preparation and Study of Lipophilic S-Nitrosothiols for Use in Improving the Biocompatibility of Medical Grade Polymers.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[S-Nitrosothiol, Nitric oxide, Biocompatibility, Biomaterials, NO Donor, RSNO, Chemistry, Science (General), Science, Chemistry]

预览 | 原文链接 [浏览：54 下载：3]
An Antibiotic Discovery Campaign Targeting VirF, the Main Transcriptional Regulator of Virulence in Shigella flexneri

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Antibiotic Discovery Campaign, Shigella, Anti-virulence, VirF, Biological Chemistry, Microbiology and Immunology, Pharmacy and Pharmacology, Chemistry, Science (General), Health Sciences, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：27 下载：28]
Combining Active Site and Allosteric Inhibitors to Study Protein Tyrosine Kinases

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[bivalent kinase inhibitors, synergy between allosteric and active site inhibitrs, Biological Chemistry, Pharmacy and Pharmacology, Chemistry, Science (General), Health Sciences, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：10 下载：13]
In Situ Polymerization via an Environmentally-borne Initiation Stimulus.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Polymers, Oxygen-mediated polymerization, Self-healing materials, Hydrogels, Engineering (General), Materials Science and Engineering, Chemistry, Science (General), Engineering, Science, Macromolecular Science and Engineering]

预览 | 原文链接 [浏览：28 下载：15]
Development & Application of Constant pH Molecular Dynamics (CPHMD ) for Investigating pH-mediated Transient Conformational States and Their Effects on Nucleic Acid & Protein Activity.

颁布单位：[University of Michigan] | 颁布时间：2015 | 实施时间：2015 | 学科分类：[Transient States, Constant pH Molecular Dynamics, Electrostatics, pH, Molecular Modeling, Chemistry, Physics, Science (General), Science, Chemistry]

预览 | 原文链接 [浏览：60 下载：47]
Development of Novel Anticancer Therapeutics: Total Synthesis of Lactimidomycin and its Analogs and Synthetic Strategies Towards Diterpene Natural Products.

颁布单位：[University of Michigan] | 颁布时间：2015 | 实施时间：2015 | 学科分类：[Organic Chemistry, Medicinal Chemistry, Lactimidomycin, Total Synthesis of Natural Products, Diterpene-Based Small Molecules, Anticancer Therapeutics, Chemistry, Science (General), Science, Chemistry]

预览 | 原文链接 [浏览：104 下载：61]
Designing Thermal Modulators for Portable GC x GC Systems.

颁布单位：[University of Michigan] | 颁布时间：2015 | 实施时间：2015 | 学科分类：[microscale thermal modulator, two dimensional gas chromatography, Thermal modulation model, MEMS, Electrical Engineering, Engineering (General), Mechanical Engineering, Chemistry, Physics, Science (General), Engineering, Health Sciences, Science, Mechanical Engineering]

预览 | 原文链接 [浏览：11 下载：1]