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Chemical Biology

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Structural Characterization of Dynamic Protein Machines by Cryo-electron Microscopy

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Electron Microscopy, Chaperones, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：55 下载：87]
Mechanistic Investigation of the Transcriptional Coactivator Med25 and its Protein-Protein Interaction Network

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Med25 AcID, Transcriptional protein-protein interactions, Natural products, protein-observed fluorine NMR, Chemical Biology, Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：29 下载：2]
Modulating the Global Conformations of c-Src Kinase

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Kinase, c-Src, Conformation, Medicinal Chemistry, Chemical Biology, Biological Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：35 下载：86]
Structure and Biochemistry of Cytochromes P450 Involved in the Biosynthesis of Macrolide Antibiotics

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Cytochrome P450, Macrolide antibiotics, Natural products, Biosynthesis, Biological Chemistry, Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：24 下载：3]
Understanding Protein Folding Mechanisms of Chaperone Proteins Using Cryo-EM

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Cryo-EM of Chaperone Proteins, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：10 下载：2]
Understanding HDAC8-Catalyzed Deacetylation:From New Substrates to Diseases

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Histone deacetylase 8, protein substrates, Chemical Biology, Acetylation, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：27 下载：17]
The PH Domain as a Mediator of G?? Effector Interactions

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Regulation of phospholipase C beta, G protein-coupled receptor kinase, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：19 下载：13]
Fluorescent Labeling, Co-Tracking, and Quantification of RNA In Cellulo.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Intracellular Single-Molecule Fluorescence Microscopy of RNA, RNA Induced Silencing Complex, microRNA, Fluorescent labeling of mRNA, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：29 下载：14]
Immobilized Enzymes: Activity, Orientation, and Stability.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Immobilized enzymes, Nitroreductase, Self-assembling monolayers, Enzyme kinetics, Enzyme stability, Enzyme orientation, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：42 下载：32]
Targeting the Activator Interaction Domain of Mediator Subunit Med25.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Protein-protein interactions, Chemical Biology, High-throughput screening, Natural Products, Transcription, Biological Chemistry, Chemistry, Science, Chemistry]

预览 | 原文链接 [浏览：38 下载：99]