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Chemical Biology

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Understanding Protein Folding Mechanisms of Chaperone Proteins Using Cryo-EM

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Cryo-EM of Chaperone Proteins, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：11 下载：2]
Dissecting Transcriptional Coactivator Binding Networks To Enable Small Molecule Modulation

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[chemical biology, protein protein interactions, transcription, peptides, drug discovery, Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：26 下载：10]
Structure and Biochemistry of Cytochromes P450 Involved in the Biosynthesis of Macrolide Antibiotics

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Cytochrome P450, Macrolide antibiotics, Natural products, Biosynthesis, Biological Chemistry, Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：29 下载：3]
Mechanistic Investigation of the Transcriptional Coactivator Med25 and its Protein-Protein Interaction Network

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Med25 AcID, Transcriptional protein-protein interactions, Natural products, protein-observed fluorine NMR, Chemical Biology, Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：33 下载：30]
Understanding HDAC8-Catalyzed Deacetylation:From New Substrates to Diseases

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Histone deacetylase 8, protein substrates, Chemical Biology, Acetylation, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：29 下载：24]
Chemical Tools to Interrogate Protein Sulfenylation by Fluorescence Microscopy and NMR.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Fluorescent probe, Bioconjugation, Cysteine redox chemistry and biology, 19F fluorine NMR probes, Chemical switch, Live-cell imaging, Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：24 下载：16]
Unlocking an HDAC Toolbox: Methods toward Understanding Isozyme-specific Activity.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Histone Deacetylase 8, Histone Deacetylase 11, HDAC, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：17 下载：11]
Targeting the Activator Interaction Domain of Mediator Subunit Med25.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Protein-protein interactions, Chemical Biology, High-throughput screening, Natural Products, Transcription, Biological Chemistry, Chemistry, Science, Chemistry]

预览 | 原文链接 [浏览：40 下载：99]
Fluorescent Labeling, Co-Tracking, and Quantification of RNA In Cellulo.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Intracellular Single-Molecule Fluorescence Microscopy of RNA, RNA Induced Silencing Complex, microRNA, Fluorescent labeling of mRNA, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：31 下载：15]
Heat Shock Protein 70 (Hsp70) Acts as a Guardian Against Multiple Cell Death Pathways.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Chemical Probes Against Hsp70 Reveal Cytoprotective Activities, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：16 下载：0]