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Chemical Biology

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Chemical Tools to Interrogate Protein Sulfenylation by Fluorescence Microscopy and NMR.

颁布单位：[University of Michigan] | 颁布时间：2016 | 实施时间：2016 | 学科分类：[Fluorescent probe, Bioconjugation, Cysteine redox chemistry and biology, 19F fluorine NMR probes, Chemical switch, Live-cell imaging, Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：21 下载：11]
Dissecting Transcriptional Coactivator Binding Networks To Enable Small Molecule Modulation

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[chemical biology, protein protein interactions, transcription, peptides, drug discovery, Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：21 下载：10]
Structures, Dynamics, and Ribozymes:An Investigation of RNA Structural Dynamics with the Hepatitis Delta Virus and Hairpin Ribozymes.

颁布单位：[University of Michigan] | 颁布时间：2014 | 实施时间：2014 | 学科分类：[Structural Dynamics of HDV and Hairpin Ribozymes, MD Simulations, Single Molecule FRET, Intracellular Interactions With RNA, Macromolecular Crowding, Biological Chemistry, Chemistry, Science (General), Science, Chemical Biology]

预览 | 原文链接 [浏览：21 下载：16]
Functional Analysis of Protein S-Palmitoylation Enzymes.

颁布单位：[University of Michigan] | 颁布时间：2015 | 实施时间：2015 | 学科分类：[Dynamic S-Acylation, Protein S-acyltransferase, Acyl-protein thioesterase, Cancer and epithelial-mesenchymal transition, Protein S-palmitoylation probes and inhibitors, Biological Chemistry, Pharmacy and Pharmacology, Chemistry, Health Sciences, Science, Chemical Biology]

预览 | 原文链接 [浏览：20 下载：21]
Structural and Thermodynamic Investigation Into the Effects of Protein Fluorination

颁布单位：[University of Michigan] | 颁布时间：2012 | 实施时间：2012 | 学科分类：[Fluorous Proteins, Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：17 下载：10]
A Two-Prong Approach for Targeting the mRNA Cap-Dependent Translation Initiation: Small Molecules and Hydrocarbon Stapled Peptides

颁布单位：[University of Michigan] | 颁布时间：2018 | 实施时间：2018 | 学科分类：[drug discovery high throughput screening, protein-protein interaction assay development, chemical biology, cap-dependent translation initiation, hydrocarbon stapled peptides targeting eIF4E interactions, protein-protein interactions, Astronomy, Atmospheric, Oceanic and Space Sciences, Biological Chemistry, Chemical Engineering, Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：16 下载：2]
Adaptation of Chemical Biology Approaches for Dissecting Disordered Protein Dynamics

颁布单位：[University of Michigan] | 颁布时间：2018 | 实施时间：2018 | 学科分类：[IDP, Intrinsically Disordered Proteins, Protein Dynamics, Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：16 下载：29]
Expanding the Repertoire of Chemical Modulators for Heat Shock Protein 70 (Hsp70):New Probes for Neurodegenerative Disease.

颁布单位：[University of Michigan] | 颁布时间：2010 | 实施时间：2010 | 学科分类：[Developing Chemical Probes for Neurodegenerative Diseases Employing Multicomponent Reactions, Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：10 下载：0]
De Novo Designed Metallopeptides to Investigate Metal Ion Homeostasis, Electron Transfer, and Redox Catalysis.

颁布单位：[University of Michigan] | 颁布时间：2015 | 实施时间：2015 | 学科分类：[metal homeostasis, electron transfer protein, laser flash photolysis, tyrosine radical, nitrite reductase, Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：4 下载：0]