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Medicinal Chemistry

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Novel Approaches to PET Imaging Neuroinflammation

颁布单位：[University of Michigan] | 颁布时间：2019 | 实施时间：2019 | 学科分类：[PET imaging, Neuroinflammation, Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：27 下载：2]
Modulating the eIF4E-eIF4G Protein-Protein Interaction in Human Disease

颁布单位：[University of Michigan] | 颁布时间：2019 | 实施时间：2019 | 学科分类：[cap-dependent translation, Biological Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：19 下载：2]
The Design, Synthesis, and Pharmacological Evaluation of Bifunctional Mu-/Delta-Selective Opioid Receptor Ligands for the Treatment of Pain

颁布单位：[University of Michigan] | 颁布时间：2018 | 实施时间：2018 | 学科分类：[Opioid, Peptidomimetic, Medicinal chemistry, Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：29 下载：17]
Structural Investigation of Binding Events in Proteins

颁布单位：[University of Michigan] | 颁布时间：2018 | 实施时间：2018 | 学科分类：[Protein flexibility, Protein structure database, Protein-ligand binding, Protein-protein interaction (PPI), Biological Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：20 下载：12]
Synthesis and Evaluation of GAT-1 Selective PET Probes

颁布单位：[University of Michigan] | 颁布时间：2018 | 实施时间：2018 | 学科分类：[GABA, transporter, medicinal chemistry, fluorine-18, positron emission tomography, neuroimaging, Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：39 下载：21]
Development of novel PROTAC Small-Molecule Degraders of MDM2 Protein and Peptidomimetic Inhibitors Targeting WDR5-MLL1 Protein-Protein Interaction

颁布单位：[University of Michigan] | 颁布时间：2018 | 实施时间：2018 | 学科分类：[MDM2 PROTAC, Molecular glue, WDR5 Inhibitor, Science (General), Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：18 下载：8]
Functional Analysis of Early Core Region Modification in the LPS of Gram-negative Bacteria

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Lipopolysaccharide, Gram-negative, Membrane sciences, Glycolipids, Biological Chemistry, Microbiology and Immunology, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：52 下载：19]
Insights into the Mechanistic and Regulatory Properties of D-arabinose-5-phosphate

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[D-arabinose-5-phosphate isomerase, D-arabinose-5-phosphate, Biological Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：31 下载：0]
Positron Emission Tomography Radiochemistry: Improved Methodology and a Novel PET Imaging Agent for the Dopamine D3 Receptor

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[Positron Emission Tomography, Radiochemistry, Fluorine-18, Dopamine Receptors, D3 Receptors, Green Chemistry, Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：78 下载：2]
Identification and Evaluation of Bacterial RNA Polymerase Inhibitors Using a Novel Plasmid-based Transcription Assay

颁布单位：[University of Michigan] | 颁布时间：2017 | 实施时间：2017 | 学科分类：[RNA polymerase, transcription, drug discovery, rifampin, high-throughput screen, tuberculosis, Biological Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：36 下载：6]