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Biological Chemistry

2014

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Substrate Recognition and Activation by Two Flavoenzymes Involved in Pyrimidine Metabolism:Flavin-Dependent Thymidylate Synthase and tRNA-Dihydrouridine Synthase.

颁布单位：[University of Michigan] | 颁布时间：2014 | 实施时间：2014 | 学科分类：[Mechanistic enzymology, Flavin, Pyrimidine, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：31 下载：25]
Probing the Determinants of the Molecular Recognition in Metal-Dependent Deacetylase.

颁布单位：[University of Michigan] | 颁布时间：2014 | 实施时间：2014 | 学科分类：[Metal selectivity of Histone Deacetylase 8, Biological Chemistry, Science, Chemical Biology]

预览 | 原文链接 [浏览：8 下载：0]
Molecular Interactions between Various Model Cell Membranes and Membrane Active Peptides Studied by Sum Frequency Generation Vibrational Spectroscopy.

颁布单位：[University of Michigan] | 颁布时间：2014 | 实施时间：2014 | 学科分类：[Sum Frequency Generation, Vibrational Spectroscopy, Model Cell Membrane, Antimicrobial Peptides, Escherichia Coli, Lipopolysaccharide, Biological Chemistry, Chemistry, Science, Chemistry]

预览 | 原文链接 [浏览：55 下载：17]
The Role of Topological Constraints in RNA Tertiary Folding and Dynamics.

颁布单位：[University of Michigan] | 颁布时间：2014 | 实施时间：2014 | 学科分类：[RNA folding, RNA dynamics, Secondary structure, tRNA, Biological Chemistry, Chemistry, Physics, Science, Biophysics]

预览 | 原文链接 [浏览：43 下载：25]
Single-Molecule Microscopy Studies of Interactions between Alzheimer's Amyloid-(1-40) and Amyloid-(1-42) on the Membrane.

颁布单位：[University of Michigan] | 颁布时间：2014 | 实施时间：2014 | 学科分类：[Alzheimer", Amyloid-beta, Single Molecule Microscopy, In Vivo Imaging, Protein Membrane Interactions Aggregation, Biological Chemistry, Physics, Science, Biophysics]

预览 | 原文链接 [浏览：21 下载：29]
Development of Small Molecule Replication Inhibitors Against Western Equine Encephalitis Virus.

颁布单位：[University of Michigan] | 颁布时间：2014 | 实施时间：2014 | 学科分类：[alphavirus, antivirals, Biological Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：41 下载：16]
Mapping, Tracking and Modeling the Movements of Single Membrane-Bound Transcription Activator Proteins in Live Vibrio cholerae.

颁布单位：[University of Michigan] | 颁布时间：2014 | 实施时间：2014 | 学科分类：[Single-molecule Tracking, Super-resolution Fluorescence Microscopy, Biophysics, Vibrio Cholerae, Membrane-bound Transcription, Plasmon-enhanced Fluorescence, Biological Chemistry, Chemistry, Microbiology and Immunology, Physics, Science (General), Science, Chemistry]

预览 | 原文链接 [浏览：32 下载：2]
Structure-Based Design, Synthesis and Evaluation of Novel and Selective Small-Molecule Inhibitors of the Anti-Apoptotic Protein Mcl-1.

颁布单位：[University of Michigan] | 颁布时间：2014 | 实施时间：2014 | 学科分类：[Anti-apoptotic Mcl-1, Medicinal Chemistry, Protein-protein Interaction Inhibitor, Cancer, Protein NMR Spectroscopy, Structure-activity Relationship, Biological Chemistry, Chemistry, Science, Medicinal Chemistry]

预览 | 原文链接 [浏览：24 下载：28]
Structural Analysis of Mechanism and Regulation of Glutamine Amidotransferases.

颁布单位：[University of Michigan] | 颁布时间：2014 | 实施时间：2014 | 学科分类：[glutamine amidotransferases, X-ray crystallography, Biological Chemistry, Science, Biological Chemistry]

预览 | 原文链接 [浏览：21 下载：11]
Mechanism of Nucleotide Flipping by Human Alkyladenine DNA Glycosylase.

颁布单位：[University of Michigan] | 颁布时间：2014 | 实施时间：2014 | 学科分类：[Kinetic mechanism of a DNA repair protein, Biological Chemistry, Science, Biological Chemistry]

预览 | 原文链接 [浏览：5 下载：0]