Submacular Choroid Thickness Increases During Long-Duration Spaceflight

[摘要] The Spaceflight Associated Neuro-ocular Syndrome (SANS) is characterized by the development of optic disc edema, choroidal folds, cotton-wool spots, globe flattening, and/or refractive error changes greater than or equal to 0.75D during long-duration spaceflight to the International Space Station (ISS). It is hypothesized that these findings result from the headward fluid shift that occurs due to weightlessness. We can induce a headward fluid shift on Earth using positional changes and on ISS due to weightlessness. Lower-body negative pressure (LBNP) is used to reverse the headward fluid shift by drawing fluid into the lower body and can be used on Earth and on ISS.

[发布日期] 2018-04-28

[学科分类] 原子、分子光学和等离子物理

[关键词] LOWER BODY NEGATIVE PRESSURE;SIGNS AND SYMPTOMS;INTERNATIONAL SPACE STATION