Multistage Delivery of Active Agents

[摘要] Multistage delivery vehicles are disclosed which include a first stage particle and a second stage particle. The first stage particle is a micro or nanoparticle that contains the second stage particle. The second stage particle includes an active agent, such as a therapeutic agent or an imaging agent. The multistage delivery vehicle allows sequential overcoming or bypassing of biological barriers. The multistage delivery vehicle is administered as a part of a composition that includes a plurality of the vehicles. Methods of making the multistage delivery vehicles are also provided.

[发布日期] 2018-12-04

[学科分类] 生物科学（综合）

[关键词] DISEASES;DRUGS;IMAGING TECHNIQUES;MOLECULAR STRUCTURE;NANOPARTICLES;RADIATION THERAPY;RESERVOIRS;TARGETS;THERAPY;PATENTS;CANCER;HEALTH;INFECTIOUS DISEASES;NANOTECHNOLOGY;SEMICONDUCTORS (MATERIALS);SILICON DIOXIDE