Molecular Engineering of Technetium and Rhenium Based Radiopharmaceuticals

[摘要] The research was based on the observation that despite the extraordinarily rich coordination chemistry of technetium and rhenium and several notable successes in reagent design, the extensive investigations by numerous research groups on a variety of N{sub 2}S{sub 2} and N{sub 3}S donor type ligands and on HYNIC have revealed that the chemistries of these ligands with Tc and Re are rather complex, giving rise to considerable difficulties in the development of reliable procedures for the development of radiopharmaceutical reagents.

[发布日期] 2003-06-30 [发布机构] Syracuse University (United States)

[关键词] Radiopharmaceuticals;Rhenium;62 Radiology And Nuclear Medicine;Technetium;Design