Impedance measurement platform for impedimetric biosensor

[摘要] Measuring proteins in blood is particularly common such as in PSA, to determine prostate function and in many other bio-applications. Today this process is inconveniencing in that it requires a lot of blood from the patients for tests to be made. Furthermore it is time consuming and expensive since samples are transferred to a central lab where tests are carried out on optical assays. Using electrical read out methods several measurements can be multiplexed and a differential measurements made. With a differential measurement the precision of the system is improved by cancelling out common mode bio-chemical noise. The multiplexed measurement enables measurement of several analytes. Using the embedded system MAX32600, an electrical impedance meter was designed that measures three impedances simultaneously with accuracy range of up-to 1% and precision of 0.2% of the actual impedance measured from an Impedance analyzer.

[发布机构] Massachusetts Institute of Technology