FIBROUS PROTEINS OF EPIDERMIS

[摘要] Extraction of guinea pig, frog and human epidermis with urea or acid buffer at pH 2.65 yielded a number of proteins. A characteristic fibrous protein could be isolated from each of the tissues by repeated precipitation at pH 7.0. X-ray diffraction analyses of fibers and films prepared from guinea pig fibrous protein showed an a pattern while those from the frog gave a cross /3 pattern while whole epidermis revealed both a and cross /3 components. The evidence suggested that the cross j3 protein is an altered a but its presence as a unique protein in the epidermis can not be excluded.