A NEW FIXATIVE FOR CUTANEOUS HISTOPATHOLOGY

[摘要] Aqueous solution of 8% neutralized formalin with 1% nickel nitrate is described and recommended as a fixative (Formalin-Nickel) in cutaneous histopathology. It is a good fixative for routine work, since it is handled easily and rapidly: can be preserved indefinitely, and produces good staining of the epidermis and the dermis (H-E; Mallory, Giemsa Van Gieson, Mayer''s hema-lum; Regaud''s and Heidenhain''s iron-hematoxylin; etc.). It is an excellent fixative of elastic fibers, assuring investigation of these fibers with excellent staining (Weigert, Gomory, Taenzer-Unna, etc.) and detail. It is a certain fixative of the neurovegetative system of the skin. It allows one to keep the biopsy specimens for many years without changing their capacity for silver staining.