DEMONSTRATION BY ELECTRONMICROSCOPY OF AN INTRANUCLEAR VIRUS IN EPIDERMODYSPLASIA VERRUCIFORMIS

[摘要] Epidermodysplasia verruciformis should be regarded as a genodermatosis in which the anomaly of the skin finds its expression in a demonstrable decrease in resistance to a virus, which is presumably identical or related to that of verrucae vulgares. In addition, several authors nave drawn attention to the fact that these cutaneous lesions, in contrast to those of verrucae vulgares, show a distinct tendency to malignant degeneration at a comparatively young age, probably because of the special nature of the terrain, i.e. the genetically affected skin in which the lesions develop. Hence, it is clear that it is not appropriate to use the designation verrucosis generalissata for the genodermatosis epidermodysplasis verruciformis.