CUMULATIVE EFFECTS FROM REPEATED EXPOSURES TO ULTRAVIOLET-RADIATION

[摘要] Repeated exposures to subliminal doses of UVR [UV radiation], given at 24 h intervals, resulted in a lowering of the erythema threshold dose. At erythemogenically equivalent doses, UV-A [longwave UV] was the most effective and UV-C [shortwave UV] the least. A similar and more pronounced effect was observed following repeated exposures to subthreshold doses of UV-A and topically applied 8-methoxypsoralen. These findings provided quantitative evidence for the cumulative nature of acute UVR damage in human skin.