BIOCHEMICAL EFFECTS OF DIHYDROXYACETONE

[摘要] Dihydroxy-acetone (DHA) can be demonstrated in blood streams of patients following external application. DHA crosses the skin membrane in isolated rat skin. Rat skin homogenates incubated with DHA accumulate lactic acid. DHA seems to be metabolized along normal pathways by skin homogenates. Glycine and alanine are decreased in skin homogenates incubated with DHA. Rat adipose tissue incubated with DHA accumulates an unidentified metabolite which interferes with lactic acid determinations.