OBSERVATIONS ON THE EFFECT OF CORTISONE IN ACNE VULGARIS

[摘要] Seventeen patients with acne vulgar is (8 males and 9 females) were given one or more courses of cortisone in doses averaging 25 mg daily for periods of 10-28 days in an attempt to benefit the skin by the known adrenal suppressive effect of the hormone. Patients were evaluated on a purely clinical basis as follows. Four females and 1 male noted mild to moderate suppression of oiliness and reduction in the number of comedones. This effect was temporary in 2 females and in the male. Two other females noted a prolonged suppression of comedone and papule formation after stopping cortisone, for 3 months in one and for more than 6 weeks in the other. Twelve patients noted no effect from the cortisone.