THE FUNGISTATIC ACTION OF OLEIC, LINOLEIC, AND LINOLENIC ACIDS ON TRICHOPHYTON RUBRUM INVITRO

[摘要] The unsaturated oleic (monoethenoid series), linoleic (diethenoid series), and linolenic (triethenoid series) fatty acids have been investigated in vitro for their fungistatic activity on Trichophyton rubrum. It was found that oleic acid had very slight fungistatic action in a 1:10 concentration; linoleic acid had slight to moderate fungistatic action in concentrations from 1:1000 to 1:10; linolenic acid had moderate to substantial fungistatic action in concentrations of 1:1000 to 1:10; while undiluted acetone, under the same conditions, did not inhibit growth of the fungus at all.