IMMUNOHISTOCHEMICAL STUDY OF HUMAN MALIGNANT MELANOMA FOR PRESENCE OF GAMMA GLOBULIN

[摘要] The distribution of gamma globulin in 13 human malignant melanomas Including those of a patient with involuting lesions, was studied by the fluorescent antibody method. Seven of the malignant melanomas contained gamma globulin In plasma cells and/or large mononuclear cells. Gamma globulin was not detectable In or on the tumor cells. No gamma globulin which would bind to sections of their own tumors was found in the serums of patients with malignant melanoma.