CHEMICAL GROUPINGS RESPONSIBLE FOR DELAYED TYPE INTRADERMAL REACTIONS TO PROCAINE

[摘要] Four of seven patients showing delayed type intradermal reactions to procaine had delayed intradermal reactions to para-amtoobenzoic acid. The remaining 3 patients reacted only to a mixture of para-amtoobenzoic acid and 2-diethylaminoethanol suggesting that an additional allergenic determinant group to the side-chain was essential for the allergic reaction to the second category of patients.