Tumor Evasion May Occur via Expression of Regulatory Molecules: A Case for CTLA-4 in Melanoma

[摘要] Emerging data that show immune-regulating molecules may be ectopically expressed on human tumors suggest that novel mechanisms may induce tumor-related immune suppression, and support the use of antibodies and small molecules to target those immune-suppressive moities.

[发布日期] 2008-12-01