THE GROWTH IN THE DEVELOPING CHICKEN EMBRYO OF A FILTRABLE AGENT FROM VERRUCA VULGARIS

[摘要] An agent was obtained from a human wart which caused massive proliferation and pearl formation when inoculated on the choria-allantoic membrane (CAM) of 10-day-old chick embryos. Some virus was present in the liver and allantoic fluid of affected embryos, but it was much more concentrated in the CAM. It was readily filterable through a Berkefeld V candle but not at all through a Boerner filter pad. No virus-neutralizing antibodies were demonstrated in the patient''s serum. The agent was somewhat susceptible to the action of Terramycin, aureomycin, and phenyl mercuric /nitrate but not to streptomycin.