HEALING OF SKIN WOUNDS IN PRIMATES .2. PROLIFERATION OF EPIDERMAL CELL MELANOCYTES

[摘要] Small wounds were made in the scalp of rhesus monkeys and biopsy specimens were excised daily. From the 2nd to the 5th day after wounding, epidermal melanocytes, mostly round and containing a few pigment granules, were found in the advancing epithelium but not at the wound margin. From 6 to 10 days after wounding, melanocytes were found in all stages of mitosis. Damage to the skin provoked 1st a migration and then proliferation of both systems, keratinocytes and the accompanying melanocytes. Thus, the behavior of the melanocytes may depend upon the physiological condition and integrity of the surrounding epidermis.