STUDIES ON THE EFFECT OF PH AND SOLUBILITY ON THE ANTIFUNGAL PROPERTIES OF FATTY ACIDS, TRIMETHYL CETYL AMMONIUM PENTACHLORPHENATE AND OTHER AGENTS

[摘要] The growth-inhibitory activity of fatty acids and other agents against fungi may be dependent upon pH and solubility, a higher range of activity being obtained when tests are carried out in media of pH 5. With the exception of propionic acid, higher fungistatic end points are obtained when a solubilizing diluent such as 50% propylene glycol-water is used, than when water alone is used as the diluting fluid. The fungistatic activity at pH 5 is directly related to the length of the carbon chain.