SITE OF DEPOSITION AND RATE OF CLEARANCE OF SALINE AFTER SUBCUTANEOUS INJECTION INTO MOUSE TAIL

[摘要] Carbon particles of Indian ink injected apparently superficially into the tail skin in the same manner as injected saline were found on histological examination to be deposited in the deep dermis, and it was not possible to inject into the dense superficial dermis. This indicates that the saline injected into the tail skin was also deposited quite deep in the dermis. Experiments with 24 Na isotope labelled saline showed that removal of Na was rapid, and this was related to the fluid removal. It was indirectly shown that reduction of fluid pressure in a saline bleb was also rapid.