SULFONE DRUGS IN DUHRINGS DISEASE - FURTHER EXPERIENCE

[摘要] The sulfone drugs have now been used for 7 years in a total of 27 patients with dermatitis herpetiformis. Of this number, 2 patients received Promacetin and the rest were given Diasone. Both drugs are effective, Diasone in smaller doses than Promacetin. Both show low toxicity and are welcome alternatives to sulfapyridine, either when the latter is not tolerated or effective, or as initial treatment. Like sulfapyridine, to be effective the sulfone drugs must continue to be exhibited to prevent relapse and remain effective without developing in the patient resistance or tolerance.