NORMAL SKIN REACTIONS TO ULTRAVIOLET LIGHT .1. AN ATTEMPT TO MODIFY NORMAL ERYTHEMA AND PIGMENTATION WITH METHOXSALEN

[摘要] No alteration was observed in the amount of UV light, either from artificial or natural sources, required to produce minimal erythema in psoralen treated subjects as compared to placebo treated controls. Methoxsalen ingestion neither inhibited nor enhanced sunburn erythema or pigmentation. There were no consistent histologic differences in the skin of subjects taking methoxsalen, versus placebo, either in sunburned or in pigmented areas.