THE RESPONSE OF THE SWEAT GLANDS TO SOME LOCALLY ACTING AGENTS IN HUMAN SUBJECTS

[摘要] Prostigmine and physostigmine, by intracut. injn., induce local sweating and potentiate the response to acetylcholine. This indicates that acetylcholine is constantly being produced in sub-threshold amts. and that the anticholinesterases permit it to build up above threshold levels. Epinephrine, prostigmine, physostigmine and histamine combined with acetylcholine failed to produce sweat response in denervated glands. The threshold dose of acetylcholine producing sweating is higher in females than in males.