THE PROPERTIES OF THE RECEPTORS IN THE AXON REFLEX SWEATING PRODUCED BY NICOTINE AND SODIUM CHLORIDE

[摘要] The minimal effective concns. of 19 blocking agents for completely suppressing the axon reflex sweating produced by nicotine and NaCl, at the site of the receptors are descr. Tetraethylammonium, hexamethonium and decamethonium blocked the sweat response to nicotine without interfering with the response to NaCl. The presence of Na ions in the external medium of the axon reflex receptors is necessary for eliciting the sweat response to nicotine. The axon reflex sweating was produced also in cat''s toe pad by intradermal injn. of nicotine and NaCl: at about 70-76 hrs. after section of postganglionic sympathetic sweat fibers, the axon reflex sweating could no longer be elicited.