VDRL CHANCROID STUDIES .2. EXPERIMENTAL CHANCROID IN THE RABBIT

[摘要] A total of 256 intradermal inoculations were made with cultures of 4 strains of Hemophilus ducreyi. These injections were made into the back and abdominal regions of 16 young rabbits. All inoculations produced lesions. However, the size and intensity of the lesion depended upon the dose, virulence of the strain of organism employed, and upon the individual rabbit. Repeated attempts to produce lesions in normal rabbits by rubbing virulent cultures into scarified areas met with failure in every case. In order to produce a lesion in rabbits by rubbing cultures into broken skin, previously sensitized rabbits must be used.