THE EFFECT OF SALICYLAZOSULFAPYRIDINE (AZULFIDINE) ON PUSTULAR ACNE VULGARIS AND CERTAIN OTHER DERMATOSES

[摘要] Salicylazosulfapyridine had a beneficial effect in over half of 68 cases of various dermatoses. Its advantage over sulfapyridine is its lesser toxicity, and over the broad spectrum antibiotics, its lesser cost. It is not superior to sulfapyridine for cases of dermatitis herpetiformis. Some failures were due to the lower dosage of the drug (2 g/day). A superior response was achieved consistently with a larger dose (4 g/day). Salicylazosulfapyridine is a definite adjunct in the control of the pustular phase of acne vulgaris and of several other dermatoses which have an infectious element, but does not influence the underlying pathologic defect. If the dose is high or is to be maintained for long, periodic blood counts and urinanalysis are essential.