INCREASED MICRO-VASCULAR WATER FILTRATION AND BLOOD-FLOW IN EXTENSIVE SKIN-DISEASE

[摘要] The rate of microvascular fluid transfer was estimated in 11 patients with extensive skin disease from the capillary filtration coefficient as measured by strain-gauge plethysmography on the forearm. Capillary filtration of the patients was significantly increased when compared with the control group (P < 0.001). Blood flow was increased to the same extent as capillary filtration, resulting in a normal mean ratio between the capillary filtration coefficient and the blood flow. An increased capillary surface area available for exchange of fluid can explain the increased microvascular water filtration.