THE IMMEDIATE WHEAL AND THE 24-48 HOUR TUBERCULIN TYPE EDEMATOUS REACTIONS TO TRICHOPHYTIN

[摘要] Urticarial reactions to trichophytin were observed in patients with Trichophyton rubrum infections, in patients with a history of atopy, and in patients with recurrent lymphangitis. No one of these factors was constantly present. The tuberculin type of sensitivity was abolished in all of the 12 patients given intradermal injns. of trichophytin. The urticarial type of sensitivity was not abolished by such injns. in 2 patients who showed it before treatment, and it developed in 3 additional patients at about the time their tuberculin type of sensitivity disappeared. An intense edematous type of somewhat delayed reaction was observed during the course of immunization in some cases. Time and a constant supply of antigen are believed to be important factors in the production of the wheal reaction to trichophytin.