PENETRATION OF RADIOIODIDE (I-31) THROUGH HUMAN SKIN

[摘要] The ability of radioactive iodide (I131) to penetrate the skin was tested, using a patch test technique. One group of subjects was tested on the forearm, the other on the palmar skin. About 2% of the I131 applied to the forearm passed the skin barrier and was detected in the thyroid and the urine. Penetration of I131 through the palmar skin was also demonstrated, being about 1/3 of the penetration through the skin of the forearm. Radioiodide simply dropped on the skin and allowed to dry penetrated in traces. About 7% of the dose applied to the forearm and about 13% of the dose on the palm remained in the superficial layers of the skin for a period of at least 48 hours.