EXPERIMENTS IN THE SWEATING ON THE PALMS OF THE GREEN MONKEY (CERCOPITHECUS-AETHIOPS)

[摘要] Spontaneous sweating ceased immediately after the nerves to the hands were severed at wrist portion in green monkey. Sweating began to reappear 10 weeks after denervation and was fully restored after 15 weeks. After denervation, mecholyl became increasingly less effective and failed to induce sweating after 1 week. Ten weeks after the operation, when the glands were clearly reinnervated, the sweat response to mecholyl became somewhat more evident than that before the denervation. The behavior of the glands in the response to adrenaline in normal and operated hands, and that before and after reinnervation had occurred are similar to those in the response to mecholyl. The axon reflex mechanism produced by nicotine disappears within 4 days after denervation. The glands were found to be surrounded by nerves rich in both acetylcholinesterase and butyrylcholinesterase. These enzymes disappeared in about 4 days after denervation and re-appeared after 10 weeks, when the glands became again functional and reactive to sudorific drugs.