ACID NUCLEASES IN HUMAN SKIN

[摘要] Both DNase and RNase are present in human epidermal cells. Although there is some evidence that activity may be scattered throughout the cells, the main reaction site appears related to the cell nucleus. De Duve classified both acid RNase and the acid DNase as lysosomal in origin; this is, therefore, additional circumstantial evidence for the existence of these bodies in human epidermis. The function of these enzymes would be to remove the nucleic and also perhaps the cellular ribosomes during the normal process of keratinization.