METHODS FOR THE RAPID EVALUATION OF THE BENEFICIAL AND HARMFUL EFFECTS OF AGENTS APPLIED TO THE HUMAN SKIN

[摘要] Standard procedures for the evaluation include in vitro detn. of the ability of the vehicle to deliver the active agent, preliminary estimation of the degree of irritancy, actual testing for the relative efficacy, extensive testing for irritancy and allergenic qualities, evaluation of the effect of aging, temperature, container, etc., other factors as suitable packaging and general acceptability of the end product to the user.[long dash]R. L. Mayer.