EFFECT OF X-RAYS ON SEBACEOUS GLANDS OF THE HUMAN FACE - RADIATION THERAPY OF ACNE

[摘要] While the large sebaceous glands of the human cheek are relatively radiosensitive, being moderately suppressed by a dose of 400r, these glands have a tremendous potential for regeneration. After administration of 1200r in fractional dosages, recovery is complete in 4 months. Even after a single dose of 1500r there is considerable sebaceous regeneration at 1 year. The effect of X-ray therapy on the acne process is mediated through sebaceous glands suppression; it is not anti-inflammatory. The most satisfactory results are obtained with prolonged fractional therapy of 75r per week thereby suppressing the glands for a longer period. Clinical remission is usually temporary; acne recurs when the glands regenerate.