IFITMs Restrict the Replication of Multiple Pathogenic Viruses

[摘要] The interferon-inducible transnnembrane protein (IFITM) family inhibits a growing number of pathogenic viruses, among them influenza A virus, dengue virus, hepatitis C virus, and Ebola virus. This review covers recent developments in our understanding of the IFITM's molecular determinants, potential mechanisms of action, and impact on pathogenesis. (C) 2013 Elsevier Ltd. All rights reserved.

[发布日期] 2013-12-13

[关键词] interferon effector genes