Rodent models used in preclinical studies of deep brain stimulation to rescue memory deficits

[摘要] Deep brain stimulation paradigms might be used to treat memory disorders in patients with stroke or traumatic brain injury. However, proof of concept studies in animal models are needed before clinical translation. We propose here a comprehensive review of rodent models for Traumatic Brain Injury and Stroke. We systematically review the histological, behavioral and electrophysiological features of each model and identify those that are the most relevant for translational research.

[发布日期] 2021-11-01

[关键词] Traumatic Brain Injury;Stroke;Rodent;Deep Brain Stimulation;Memory