Galanin: A potential role in mesolimbic dopamine-mediated instrumental behavior

[摘要] The involvement of the neuropeptide galanin in the consumption of the primary commodities of food and water is well established. However, the present review describes anatomical and behavioral evidence that suggests that galanin may also modulate ascending mesolimbic dopamine function and thereby play an inhibitory role in the systems by which instrumental behavior is energized toward acquiring primary commodities. General anatomical frameworks for this interaction are presented and future studies that could evaluate it are discussed. (c) 2008 Elsevier Ltd. All rights reserved.

[发布日期] 2008-10-01

[关键词] Drinking;Galanin;Feeding;Progressive ratio;Consumption;Motivation