The current and future perspectives of zinc oxide nanoparticles in the treatment of diabetes mellitus

[摘要] Diabetes mellitus (DM) is a multifaceted and costly disease, which requires serious attention. Finding a cheaper anti-diabetic alternative that can act on multiple disease-related targets and pathways is the ultimate treatment goal for DM. Nanotechnology has offered some exciting possibilities in biomedical and drug delivery applications. Zinc oxide nanoparticles (ZnO-NPs), a novel agent to deliver zinc, have great implications in many disease therapies including DM. This review summarizes the pharmacological mechanisms by which ZnO-NPs alleviate DM and diabetic complications. Research implications and future perspectives were also discussed.

[发布日期] 2019-12-15

[关键词] Diabetes mellitus;Hyperglycemia;Hypoglycemic agents;Insulin;Nanoparticles;Zinc oxide