Case study and review: Treatment of tricuspid prosthetic valve thrombosis

[摘要] Prosthetic valve thrombosis (PVT) is a severe and life-threatening complication of heart valve replacement. Conventional therapy is surgical thrombectomy or valve replacement. Medical thrombolysis is another emerging option. We report the case of a 57 year old woman with a history of Ebstein anomaly who underwent successful treatment of tricuspid prosthetic valve thrombosis with intra-atrial infusion of very low dose recombinant tissue plasminogen activator (tPA). We review the presentation, etiology, diagnosis, and treatment of tricuspid PVT emphasizing a modified medical option as a safe, minimally invasive alternative to surgical intervention or conventional medical therapy for tricuspid valve thrombosis. Published by Elsevier Ireland Ltd.

[发布日期] 2012-12-15

[关键词] Tricuspid valve;Prosthetic valve;Thrombosis, thrombolysis, fibrinolysis;Ebstein anomaly;Recombinant tissue plasminogen activator (tPa);Pannus