Congenital estrogen deficiency in men: a new syndrome with different phenotypes; clinical and therapeutic implications in men

[摘要] The report focuses on the role of estrogens in human male, dealing with two human models of congenital estrogen deficiency: estrogen resistance and aromatase deficiency. Similarities and differences of clinical phenotypes of these models are described and progresses of estrogen treatment of aromatase-deficient men are reported. Finally, the putative use of estrogen in men and the use of aromatase inhibitors and antiestrogen for male disorders are discussed. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

[发布日期] 2002-07-31

[效力级别]  Proceedings Paper

[关键词] estrogen deficiency;bone maturation;eunuchoid skeleton;male osteoporosis;estrogen replacement therapy;growth disorders;aromatase inhibitors;male estrogen treatment